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A 65-year-old man is brought to a sleep clinic by his wife. She reports that for the past year, he has been shouting, kicking, and flailing his arms during sleep, seemingly acting out vivid dreams. His medical history is significant for a recent diagnosis of Parkinson's disease and a long-standing prescription for an antidepressant. Based on this information, which factor is the most direct and significant contributor to his predisposition for this specific sleep disturbance?
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A 65-year-old man is brought to a sleep clinic by his wife. She reports that for the past year, he has been shouting, kicking, and flailing his arms during sleep, seemingly acting out vivid dreams. His medical history is significant for a recent diagnosis of Parkinson's disease and a long-standing prescription for an antidepressant. Based on this information, which factor is the most direct and significant contributor to his predisposition for this specific sleep disturbance?