An episode where the electrical activity in the brain is synchronized, causing the brain to excite continuously. It is seen in EEGs as a "spike and wave" pattern.

Seizures

Neuromuscular junction (NMJ) electrophysiology is performed on Drosophila third instar larvae to study human diseases characterized by abnormal electrophysiology, such as epilepsy and ALS. The larva is fileted down the length of its body to expose the ventral nerve cord and body wall muscles. Electrodes are then inserted into a motor neuron and a corresponding body wall muscle. This method of studying the NMJ is accurate, but difficult and labor-intensive, so electrophysiology is combined with genetic screens to fully characterize NMJ mutations.

Neuromuscular Junction Electrophysiology

Abnormalities in neurophysiology refer to abnormalities in the transmission of electrical and chemical signals in the nervous system, which may be involved in a wide variety of medical conditions. 

Grinnell College

Brandeis University

The study of how information is transmitted throughout the nervous system using electrical and chemical signals.

Neurophysiology

Breedlove, S. & Watson, N. (2017). Behavioral neuroscience, eighth edition. Oxford University Press.

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