Because of the blood brain barrier, there is no normal microbiota in the spinal fluid.

University of Wisconsin - Madison

Tight cell junctions of the blood vessel endothelia of the central nervous system, which prevent microbes from entering the bloodstream leading to the brain and cerebrospinal fluid. Infection of the CNS can lead to fatal inflammation.

Blood-Brain Barrier

https://openstax.org/details/books/microbiology/

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

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