Concept

ACE2 Protein and mRNA Expression in Tissue

Expression levels were determined using the HPA (https://www.proteinatlas.org). Tissues that express ACE2 were broken down into five categories based off of the amount of ACE2 mRNA expression:

  • (1, highest expression, score range: 122-10) small intestine, colon, duodenum, kidney, testis, gallbladder and heart muscle
  • (2, medium high expression, score range: 5-1) adipose tissue, thyroid gland, epididymis, ductus deferens, breast, pancreas, rectum, ovary, esophagus, liver, seminal vesicle, salivary gland and placenta
  • (3, medium low expression, score range: 0.9-0.5) vagina, lung, appendix, skeletal muscle, fallopian tube, lymph node, tongue, stomach and prostate
  • (4, low expression, score range: 0.4-0.1) remaining tissues
  • (5, no expression, score range: 0) parathyroid gland, bone marrow, monocytes, B-cells, NK-cells, dendritic cells and total peripheral blood mononuclear cell
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Updated 2020-08-31

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SARS-CoV-2 (COVID-19)

Biomedical Sciences