Enzyme Activation Energy Diagram (Figure 8.5). Reprinted from OpenStax Microbiology (p. 300), by N. Parker, M. Shneegurt, A.-h. Thi Tu, B. M. Forester, and P. Lister, 2016, Rice University. Copyright 2016 by Rice University.

Enzyme Activation Energy Diagram

A reaction's activation energy is the amount of energy needed to drive a chemical reaction. A certain threshold of energy must be met for reactions to happen. Catalysts like enzymes work to lower activation energy and thus increase the reaction rate.

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Some features of enzyme-substrate complexes include:

- Enzyme Specificity
- Substrate
- Active Site
- Activation energy

Features of the Enzyme-Substrate Complex

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Substrate

The location on an enzyme to which a substrate binds

Active site

Enzymes are known for their specificity given their ability to change structure - modifications at the active site and formation of a transition state  - to bind substrates. This leads to an induced fit between enzyme and substrate(s).

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