Adult hookworms, located in the host’s GI tract, will continuously ingest blood that is then ruptured in the worm’s digestive system. As a result, there is a release of hemoglobin that will be broken down by a protein cascade. These proteins have been identified and the vaccination of humans with these antigens may induce antibodies that can be ingested by the worm. These antibodies would disrupt these protein cascades and the worm’s digestive pathway, reducing the likelihood that the adult hookworm will survive.