Cocaine acts as an agonist in the dopamine neurotransmitter system by blocking dopamine reuptake at the neuronal synapse.

Cocaine's Mechanism of Action

An agonist is a type of drug that facilitates and enhances the activity of a particular neurotransmitter system.

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Drugs can be classified based on their action within a neurotransmitter system. They can either function as agonists, which enhance the system's activity, or as antagonists, which hinder it.

Classification of Drug Actions on Neurotransmitter Systems

Spielman, R. M., Jenkins, W. J., & Lovett, M. D. (2020, April 22). Psychology (2nd ed.). OpenStax. https://openstax.org/books/psychology-2e/pages/1-introduction

OpenStax Psychology (2nd ed.) Textbook

Agonist (Drug Action)

An antagonist is a type of drug that impedes or blocks the activity of a specific neurotransmitter system.

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