University of Michigan - Ann Arbor

- Alzheimer's disease is a progressive chronic disease. It's "a type of dementia that affects memory, thinking and behavior"; over time, these symptoms progressively interfere with daily tasks.
- It's the 6th leading cause of death. Current treatments can alleviate the symptoms but can't stop the progression of Alzheimer's.

Alzheimer's Disease

 Alzheimer's Association

Wang, T., Liu, X., Guan, J., Ge, S., Wu, M., Lin, J., & Yang, L. (2019, March 05). Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0223523419302089


Multi-target drug discovery

Multi-target drugs have displayed a higher efficacy, improved safety, and simpler administration as compared to a single target. Multi-target drugs are different in the way in that they have multiple biological targets and generally contain several main steps in target identification, validation, hits identification, and lead component optimization. 

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