ACE, a homologue of ACE 2, converts Ang I into Ang II. ACE increases the amount of Ang II, a vasoconstrictor, and decreases the amount of a vasodilator. This consequently results in increased blood pressure. A class of drugs called ACE inhibitors, which are used for treating symptoms such as high blood pressure, block the activity of ACE. ACE is generally more expressed than its homologue ACE 2.