Concept

Association study between the use of RAS inhibitors with mortality among patients with hypertension hospitalized with COVID-19

  • retrospective, multi-center study that included 1128 patients with hypertension diagnosed with COVID-19
  • of the 1128 patients, 188 were taking ACEI/ARBs
  • after adjustment for age, gender, comorbidities and in-hospital medications, the risk for mortality was found to be lower in the ACEI/ARB group vs those who weren't taking any ACEI/ARBs
  • subgroup propensity score-matched analyses revealed that ACEI/ARBs were more associated with lower mortality compared to other antihypertensive drugs
  • limitations of the study include the need to consider other confounding variables

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Updated 2021-02-28

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences