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Buprenorphine for OUD
- Reduce craving in OUD patients
- High affinity partial μ-opioid receptor agonist
- Associated with a ceiling effect with respect to the risk of respiratory depression
- Effects from additional illicit opioid use during maintenance treatment can be blocked
- Impact on craving is dose-dependent
- Must be carefully up-titrated to achieve the optimal dose for each patient to adequately suppress craving
- Therapeutic impact on dysphoria, potentially leading to improvements in quality of life
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Updated 2025-10-03
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