Milanez-Almeida, Pedro; Martins, Andrew J.; Germain, Ronald N.; Tsang, John S. (2020-02-10). "Cancer prognosis with shallow tumor RNA sequencing". Nature Medicine. 26 (2): 188–192. doi:10.1038/s41591-019-0729-3. ISSN 1546-170X. PMID 32042193. S2CID 211074147.(https://www.nature.com/articles/s41591-019-0729-3)

University of Michigan - Ann Arbor

1. Support vector machine
2. Metric learning
3. Portfolio optimization
4. Cancer prognosis

Application Areas

In late 2014, it was proven that the elastic net can be reduced to the linear support vector machine.A similar reduction was previously proven for the LASSO in 2014. The authors showed that for every instance of the elastic net, an artificial binary classification problem can be constructed such that the hyper-plane solution of a linear support vector machine (SVM) is identical to the solution {\displaystyle \beta }\beta  (after re-scaling). The reduction immediately enables the use of highly optimized SVM solvers for elastic net problems. It also enables the use of GPU acceleration, which is often already used for large-scale SVM solvers. The reduction is a simple transformation of the original data and regularization constants into new artificial data instances and a regularization constant that specify a binary classification problem and the SVM regularization constant. 
Here,  y 2 consists of binary labels -1,1 . When 2p>n it is typically faster to solve the linear SVM in the primal, whereas otherwise the dual formulation is faster. The authors referred to the transformation as Support Vector Elastic Net (SVEN),

Reduction to support vector machine

Cancer prognosis reference paper

Shen, Weiwei; Wang, Jun; Ma, Shiqian (2014). "Doubly Regularized Portfolio with Risk Minimization". Proceedings of the Twenty-Eighth AAAI Conference on Artificial Intelligence: 1286–1292. S2CID 11017740 (https://www.semanticscholar.org/paper/Doubly-Regularized-Portfolio-with-Risk-Minimization-Shen-Wang/60814c0450d453169045500d9299b458998a3540)

Portfolio optimization

Liu, Meizhu; Vemuri, Baba (2012). "A robust and efficient doubly regularized metric learning approach". Proceedings of the 12th European Conference on Computer Vision. Lecture Notes in Computer Science. Part IV: 646–659. doi:10.1007/978-3-642-33765-9_46. ISBN 978-3-642-33764-2. PMC 3761969. PMID 24013160.(https://dl.acm.org/doi/10.1007/978-3-642-33765-9_46)

Metric learning reference paper

Deep learning uses the neural networks to increase the computational work and provide accurate results. Assisting medical professionals and researchers to discover the hidden opportunities in data is one of the best things we can accomplish with Deep Learning. The possible applications of deep learning in the field of healthcare are: 

1. Drug discovery
2. Medical imaging
3. Insurance fraud
4. Alzheimer's disease
5. Genome

Reference: https://www.allerin.com/blog/top-5-applications-of-deep-learning-in-healthcare

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