Given the following case study, identify the most likely endocrine gland that is underactive and explain how its reduced hormone secretion leads to the specific symptoms described.

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A medical condition caused by reduced hormone levels from the thyroid gland. Sufferers may experience symptoms such as persistent tiredness and a frequent sensation of being cold.

Hypothyroidism

Clinical Symptom Analysis

A patient complains of persistent fatigue, unexplained weight gain, and a constant feeling of being cold, even in warm environments. These symptoms are most consistent with a dysfunction in which of the following biological processes?

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