Concept

Common Variable Immunodeficiency

  • Common Variable Immunodeficiency (CVID) is a disorder which lowers the immune systems defenses and makes patients more susceptible to infections in the lungs, sinuses, and ears
  • A 53 y/o patient with CVID was admitted with COVID-19
  • Patient was already receiving intravenous immunoglobulin (IVIG) for their CVID
  • Levels of patient’s immunoglobulin were taken upon arrival and it was noted that their IgG was normal, but IgM and IgA were low and undetectable respectively
  • Patient received additional IVIG daily as well as supplemental oxygen in the form of a nasal cannula and then intubation
  • Patient was extubated after 3 days and eventually weaned back to room air as well as discharged on day 14 due to clinical improvement
  • The paper also noted that there were 2 similar cases of CVID patients receiving supplemental IVIG in Italy who also made a similar recovery
  • It was also stated that while testing was not performed for cytokine storm syndrome, 53 y/o did develop some acute respiratory distress syndrome during their treatment

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Updated 2020-08-26

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences