Q-UEL language helps to obtain literature to help identify sequences of amino acids that are well conserved across mnay coronaviuses including 2019-nCov. It was identified that this virus corresponded to the region aroudn one of the known cleaveage sites of the SARS virus that is required for virus activation for the cell entry

Use of the Q-UEL language for the design of synthetic vaccine and prevenetative peptidomimetic anatgonistst 

The probability of peptides being able to help with therapeutics and vaccines are becoming more relevant in clinical genomics that involved patient DNA sequences. The homologies that match viral protein sequences and uses of automated probabilistic reasoning are becoming more relevant.
The Q-UEL system has helped develop a preliminary set of predictive 3D protein structures of the virus.

Theory about peptides as the base of potential therapeutic and vaccines

Attempting to identify and isolate a short section of viral protein sequences that can be used as a preliminary design proposal for a peptide synthetic vaccine and a peptidomimetic therapeutic. Published 17 Februaray 2020
https://www.sciencedirect.com/science/article/abs/pii/S0010482520300627


Santa Clara University

- Computers and viral diseases. Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS-COV-2 coronavirus

Biomedical Engineering for COVID-19 Articles from Journal of Computers in Biology and Medicine

Computers and viral diseases. Preliminary bioinformatics studies on the design of a synthetic vaccine and a preventative peptidomimetic antagonist against the SARS-COV-2 coronavirus

Learn Before

Related

Learn After