- Dexamethasone improved respiration in those with ARDS, thus reducing mortality rates
- Dexamethasone was found to decrease levels of NETs
  - Hypercoagulation in COVID-19 is a result of uncontrolled levels of NETs

Dexamethasone and COVID-19

Michigan State University

SARS-CoV-2 negatively impacts the cortisol stress response. Corticosteroid therapy is efficient in treating severe COVID-19


Corticosteroids and Treament of COVID-19

Arabi, Y. M., Chrousos, G. P., & Meduri, G. U. (2020). The ten reasons why corticosteroid therapy reduces mortality in severe COVID-19.

The ten reasons why corticosteroid therapy reduces mortality in severe COVID-19

Corticosteroid therapy involves the activated glucocorticoid receptor α

GC-GRα

Corticosteroids

The results from this study shows that there mght not be an effect of corticosteroid treatment or even a negative effect on in-hospital moratlity rates for severe and critical Covid-19 cases

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