When used in conjunction with psychotherapeutic intervention, DCS has been shown to increase the efficacy of concurrent therapy in ARFID patients.

Kalamazoo College

Medication is sometimes prescribed in conjunction with other forms of therapeutic intervention to manage anxiety, stimulate appetite, and improve treatment efficacy: 

- Olanzapine
- Mirtazapine
- Buspirone
- D-cycloserine (DCS)

Avoidant/Restrictive Food Intake Disorder (ARFID) Adjunctive Pharmacological Treatment

Bourne, L., Bryant-Waugh, R., Cook, J., & Mandy, W. (2020). Avoidant/restrictive food intake disorder: A systematic scoping review of the current literature. Psychiatry Research, 288, 112961.

Avoidant/Restrictive Food Intake Disorder: A Systematic Scoping Review of the Current Literature

Olanzapine is sometimes used in addition to therapy in ARFID patients to relieve anxiety and stimulate appetite.

Olanzapine for Avoidant/Restrictive Food Intake Disorder (ARFID)

Mirtazapine is sometimes prescribed to ARFID patients to stimulate appetite and relieve anxiety about choking, vomiting, or other somatic complications. However, high doses have a risk of increasing anxiety. 

Mirtazapine for Avoidant/Restrictive Food Intake Disorder (ARFID)

In combination with therapy, buspirone may relieve anxiety about choking, vomiting, etc. among ARFID patients.

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