This diagram displays how the Nsp3 protein contributes to the viral replication of the SARS-CoV-2 virus in host cells. 

Grand Valley State University

The N protein of the SARS-CoV-2 virus attaches to the Nsp3 protein on the replication-transcription complexes (RTC). This attachment allows the N protein to interact with viral RNA to help create virions to spread throughout the host after the RNA has been successfully replication. 

Nsp3 (Non-structural protein 3)

Khan, M. T., Irfan, M., Ahsan, H., Ahmed, A., Kaushik, A. C., Khan, A. S., Chinnasamy, S., Ali, A., & Wei, D.-Q. (2021). Structures of SARS-CoV-2 RNA-Binding Proteins and Therapeutic Targets. Intervirology, 64(2), 55–68. https://doi.org/10.1159/000513686. 

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