The DSM-5-TR outlines certain substances which are coded in numerical values to help specify the condition of; Substance / Medication-Induced Depressive Disorder. Furthermore, The following chart lists the applicable substances and states that may be coded as influential the substance-induced depressive disorder.

The specifiers that may be applied to the diagnosis are as followed:

• With Onset During Intoxication
• With Onset During Withdrawal
• With Onset After Medication Use