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Hyperpolarization is a phase of a neuron's action potential where the membrane potential becomes more negative than its resting state, reaching approximately -80mV. This increased negativity occurs after repolarization, as potassium (K+) ion channels remain open, allowing positively charged K+ ions to continue leaving the cell. This outflow of positive ions is driven by repulsion from the positively-charged sodium ions that had previously entered the cell.

Hyperpolarization

During a neuron's firing sequence, there is a brief period where the internal charge of the neuron becomes even more negative than its usual resting state. What is the primary ionic event responsible for this specific phase?

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