The eclipse phase is the interval in a viral growth curve during which viruses bind and penetrate the host cells, resulting in no detectable virions in the surrounding medium.

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Unlike the growth curve for a bacterial population, the growth curve for a virus population over its replication cycle does not follow a sigmoidal curve. It begins with inoculation, where the virus infects cells, followed by a flat eclipse phase, a burst phase, and a eventual decline.

Viral Growth Curve

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Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

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Eclipse Phase of Viral Growth

A viral burst is the simultaneous release of newly assembled virions from lysed host cells into the surrounding environment, resulting in a rapid increase in the viral population.

Viral Burst

A one-step multiplication curve is a graphical model of bacteriophage growth where host cell lysis and simultaneous virion release cause a steep rise in viral titer, followed by a decline as remaining viral particles degrade when host cells are depleted.

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