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Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19

Researchers aimed to determine the effect of remdesivir in patients with moderate COVID-19 pneumonia in a randomized phase 3 trial. Specifically, the effect of 5 or 10 days of treatment of remdesivir on clinical status was compared to the effect of standard care on clinical status. Patients who received a 10-day treatment of remdesivir did not differ significantly in their clinical status from patients who received standard care. Contrastingly, patients who received a 5-day remdesivir treatment demonstrated significantly higher odds of exhibiting a better clinical status than the patients who received standard care, but the difference in odds between the two patient groups was of uncertain clinical importance. It is important to note that patients who received remdesivir treatment were more likely to experience headache, hypokalemia, and nausea than patients who received standard care.

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Updated 2021-07-31

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SARS-CoV-2 (COVID-19)

Biomedical Sciences