Witjas, T., Kaphan, E., Régis, J., Jouve, E., Chérif, A., Péragut, J.,Azulay, J. (2007) Effects of chronic subthalamic stimulation on nonmotor fluctuations in Parkinson's disease. Movement Disorders, Volume 22, Issue 12, pages 1729-1734.

University of California, Berkeley

Chronic Subthalamic nucleus (STN) Deep Brain Stimulation (DBS) was applied on 40 patients with Parkinson's disease with mean age of 59. The pain was reduced by 84.2% a year after chronic STN (Preoperative = 1.7; Postoperative = 0.3). The outcome is sufficient for reducing the pain of the patients. However, the the multiple sources of pain are still not completely understood. Thus, it requires further investigation and attempts to operate this method on all Parkinson's disease patients.

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