• A study in Hubei Province, China found that patients who received statin had lower mortality rate of 5.2% compared to 9.4% mortality rate in patients who did not receive statin.

• In vitro and in vivo experiments demonstrated statins' ability to suppress TLR4/MyD88/NF-κB signaling and regulate NLRP3.

• 5μM of statin concentration was shown to moderately reduce the infectivity of alphacoronavirus 229E. Fluvastatin showed the greatest promise as it seemed to reduce infection in a dose-dependent process and had a IC50 value of 9.8μM. There was no sign of cell toxicity.

• Some reduction observed in replication of viral genome when 10μM Fluvastatin was given to human respiratory epithelial cells before they were introduced to betacoronavirus.