The relationship between psychological stress and susceptibility to the common cold could not be explained by other factors, including age, gender, education, weight, allergic status, health practices, the specific virus the subject was exposed to, or environmental characteristics associated with the study design.

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- Negative life events, perceived stress, negative affect were reliably associated with increased susceptibility to colds
- When only those persons without an infectious roommate were studied, both perceived stress and negative affect predicted clinical illness,  but the association between life events and illness was marginally reliable.
    - bigger sample for more reliable picture
- Negative life events were associated with greater rates of clinical illness (mediated creased symptoms among infected people), while perceived stress and negative affect were associated to increased infection


Negative Life Events, Perceived Stress, Negative Affect, and Susceptibility to the Common Cold

- One possibility is that the mechanisms are the same as in the case of infection and symotoms portrayal
- Alternatively, infection and illness may be attrib-utable to very different processes. 
   - Negative Life Events may affect susceptibility and interact differently with the body reactions to the pathogenesis of disease than that of perceived stress and negative affect

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