The constant region of the antibody molecule includes the trunk of the Y and lower portion of each arm of the Y. The trunk of the Y is also called the **Fc region**, for “fragment of crystallization,” and is the site of complement factor binding and binding to phagocytic cells during antibody-mediated opsonization.

Austin Community College

B Cells are responsible for the production of antibodies, also called immunoglobulins. Antibodies are present in both the blood and tissue fluids and are involved in the body’s defense against pathogens and toxins.

Antibodies

https://openstax.org/details/books/microbiology/

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

OpenStax Microbiology Textbook

The constant region of an antibody molecule determines its class, or isotype. The five classes of antibodies are:
- IgG
- IgM
- IgA
- IgD
- IgE

Classes of Antibodies 

Antibodies have many functions to help facilitate an adaptive immune response:
- Antibody-dependent cell-mediated cytotoxicity (ADCC)
- Opsonization
- Neutralization 
- Agglutination
- Activation of The Complement System

Functions of Antibodies

Fc Region of Antibodies

The two 'arms' of the Y-shaped antibody molecule are known as the **Fab region**, for "fragment of antigen binding." The far end of the Fab region is the variable region, which serves as the site of antigen binding.

Learn Before

Related