Figure 2: Differences in viral load in an exemplary group of patients aged 0-11 years with and without a pre-existing condition.
"Mean log10 viral loads in the healthy and the pre-existing condition categories are 5.642 and 4.408, respectively. Parametric (Welch’s t-test) and non-parametric (Mann-Whitney rank test) find a significant difference in viral loads between children that are healthy and those with a pre-existing condition (p-values 0.027 and 0.006, respectively), when testing the combined viral loads from both PCR systems. When only considering viral loads measured by cobas instruments, no significant difference is detected."
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Statistical Approach for An analysis for SARS-CoV-2 viral load by patient age
Figure 1: Utilization of LC480 and cobas test systems over the study period for An analysis of SARS-CoV-2 viral load by patient age
Figure 2: Differences in viral load in an exemplary group of patients aged 0-11 years with and without a pre-existing condition.
Figure 3: Viral loads over time in children from A) 0-9 and B) 0-19 year olds.
Figure 4. Distribution of viral loads by age group and PCR instrument.
Figure 5: Viral load by patient 10-year age strata.
Figure 6: Conditional effect of age from a Bayesian gamma regression predicting viral load from age, while adjusting for type of PCR system (LC480 or cobas).