Concept

Figure 2. Homology Modeling of the RBD Structures and Molecular Characterizations of the S1/S2 Cleavage Site of RmYN02 and Representative Beta-CoVs

"(A–D) Homology modeling and structural comparison of the RBD structures of RmYN02 and representative beta-CoVs, including (A) RmYN02, (B) RaTG13, (C) pangolin/MP789/2019, and (D) pangolin/GX/P5L/2017.

(E and F) Superimposition of the RBD structure of pangolin/MP789/2019 (E) and RmYN02 (F) with that of SARS-CoV-2. The two deletions located in respective loops in RmYN02 are highlighted using dotted cycles.

(G) Molecular characterizations of the RBD of RmYN02 and the representative beta-CoVs.

(H) Molecular characterizations of the cleavage site of RmYN02 and the representative beta-CoVs."

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Updated 2020-07-18

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SARS-CoV-2 (COVID-19)

Biomedical Sciences