- M0 - Healthy monkey infected with SARS-CoV-2 used as model control in second challenge
- M1 & M2 - Primary infected moneys, not re-infected
- M3 to M6 - Monkeys re-infected with the identical strain 28 days post primary infection
- Post Initial Challenge (dpi)
- Post Rechallenge (dpr)

University of California, Davis

A study in Beijing, China was conducted on rhesus macaques and found that the monkeys were protected against subsequent infection by the identical strain of the SARS-CoV-2 virus once they entered the early recovery phase. 28 days post primary infection, researchers re-exposed the virus to four monkeys and detected no changes in viral load. Antibody titers were elevated at 14 days post re-exposure, and no viral RNA or infected cells were found in necropsy specimens following euthanasia.

Application of Rhesus Macaques for Studying SARS-CoV-2 Virology

Bao, L., Deng, W., Gao, H., Xiao, C., Liu, J., Xue, J., ... & Qi, F. (2020). Lack of reinfection in rhesus macaques infected with SARS-CoV-2. bioRxiv.

https://doi.org/10.1101/2020.03.13.990226

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