- HC - Healthy Controls
- ERS - Early Recovery Stage
- LRS - Late Recovery Stage


- a. t-SNE plot comparing the cluster distribution of immune cells
- b. Bar plot showing the relative makeup of immune cells, 5 patients of each type sampled
- c. Pie chart showing the percentages of B cells, NK & T cells, and myeloid cells
- def. Heatmaps showing the differentially expressed genes (DEGs) of the respective cell types in HC, ERS, and LRS patients

University of California, Davis

A study conducted on 10 COVID-19 patients undergoing recovery examined the immune cell profile using a single-cell RNA sequencing technique. In comparison to healthy controls, it found that T cells and NK cells were significantly decreased and the number of myeloid cells and monocytes with high inflammatory gene expression increased. Plasma B cells were also increased to enhance production of antibodies. 

Transcriptome Profiling of COVID-19 Patients During Recovery Stage

Wen, W., Su, W., Tang, H., Le, W., Zhang, X., Zheng, Y., ... & Dong, L. (2020). Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing. Cell discovery, 6(1), 1-18.

https://doi.org/10.1038/s41421-020-0168-9

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