A class of benzaldehydes that are isolates of the fruiting body of Hericium Erinaceum. Hericenones are neurotropic compounds that are derivatives of cyathane. This compound can pass the BBB due to their low molecular weight which may beneficially impact on Alzheimer’s and Parkinson’s disease due to their impact on nerve growth factor (NGF).

Michigan State University

A species of edible mushroom that contains compounds that show potential to be used as a health treatment. It's common name comes from its long spines that resemble a lion's mane.

Lion's Mane Mushroom — Hericium Erinaceus

Meade, Elaine, et al. "Mycotherapy: Potential of Fungal Bioactives for the Treatment of Mental Health Disorders and Morbidities of Chronic Pain." Fungi and Fungal Metabolites for the Improvement of Human and Animal Life, Nutrition and Health, vol. II, 11 Mar. 2022, doi:https://doi.org/10.3390/jof8030290.

Mycotherapy: Potential of Fungal Bioactives for the Treatment of Mental Health Disorders and Morbidities of Chronic Pain

Well-documented medical benefits include, but aren't limited to, anticancer, antioxidative, anti-inflammatory activity, and antimicrobial activity. Due to the presence of Hericenones and Erinacines in H. Erinaceus, they may also may beneficially impact on Alzheimer’s and Parkinson’s disease, as well as depression and isochemic stroke.

Hericium Erinaceus Therapeutic Application

Hericenones

Like Hericenones, this compound can be isolated from Hericium Erinaceus. They belong to the group of cyathin diterpenoids, and have shown potential to promote NGF biosynthesis in humans which may beneficially impact on ischemic stroke, depression, Alzheimer’s and Parkinson’s disease. This compound can pass the BBB due to their low molecular weight.

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