- HD is inherited in an autosomal dominant manner (i.e., one mutant copy of the gene is enough to cause symptoms).
- Inheritance is independent of gender.

University of Michigan - Ann Arbor

- Inherited in an autosomal dominant manner (i.e., one mutant copy of the gene is enough to cause symptoms)
- CAG segment in the gene Huntington is repeated too many times, leading to the formation of an abnormal huntington protein

Genetics of Huntington's Disease

Medline Plus | U.S. National Library of Medicine

Huntington's Disease Society of America

How is Huntington's Disease (HD) inherited?

- The CAG DNA segment in the gene huntingtin is repeated too many times.
- The gene huntingtin is on the short arm of chromosome 4.
- Please see the image below from the U.S. National Library of Medicine for more details.

Learn Before

Related