Miami University of Ohio

Since it is difficult to pinpoint any one gene responsible for schizophrenia, genetic analyses has found more than 100 genes that influence the development of schizophrenia. Some of them are as follows:

Individual Genes involved in Schizophrenia 

Breedlove, S. & Watson, N. (2017). Behavioral neuroscience, eighth edition. Oxford University Press.

Behavioral Neuroscience 8th Edition

It is involved in receptor regulation of NMDA (N-Methyl-d-Aspartate), GABA (Gamma-Aminobutyric Acid) and ACh (Acetylcholine)

Genes encoding Neuregulin 1

Individual Genes: Dysbindin

It participates in metabolizing dopamine.

Individual Genes: Catechol-O-methyltransferase (COMT):

Normally, DISC1 protein interacts with other proteins during brain development. Unregulated expression of DISC 1 may predispose people to the development of schizophrenia

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