- Acetylcholine is depleted in AD brains
- Inhibition of acetylcholinesterase (degrading enzyme) aims to improve cholinergic neurotransmission
- Studies have shown beneficial effects from this type of treatment but it is now shown to reverse AD

Michigan State University

- Inhibitors of acetylcholinesterase
- Antagonist of a receptor for the neurotransmitter glutamate
- Drugs to control depression and behavioral abnormalities

Treatments for Alzheimer's Disease

Mucke, L. Alzheimer's disease. Nature 461, 895–897 (2009). https://doi-org.proxy2.cl.msu.edu/10.1038/461895a

Alzheimer's Disease 

Inhibitors of Acetylcholinesterase

The risk of developing Alzheimer's disease can be mitigated through various lifestyle and environmental considerations. Nutritional strategies, such as adopting a Mediterranean diet, are associated with a lower risk. Managing environmental factors is also crucial, as exposure to substances like lead, iron, and zinc can increase risk. Additionally, a healthy diet to manage cholesterol and blood pressure, regular physical exercise, social engagement, and mental activity are all believed to be protective.

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