Apoptosis, which is essentially cell death that is triggered by certain factors, is an important mechanism in the antiviral immune response as it allows the killing of infected cells which aids in limiting and controlling the infection as well as playing a regulatory role in inflammation. Multiple accessory proteins seem to affect apoptosis of host cells and contribute to viral pathogenesis by doing so, making apoptosis an overlapping and overarching concept regarding accessory protein of SARS-CoV2.