During the COVID-19 pandemic, social distancing and remote education increased social isolation and loneliness, especially among young adults and college students. Loneliness is linked to adverse psychological consequences, including a higher risk of stress, anxiety, depression, and suicide. Because prior research identified social support, personal resilience, and coping abilities as protective factors against stress, a study was conducted to evaluate the effect of coping behaviors, resilience, and social support on loneliness in college students during the COVID-19 pandemic and resulting lockdowns.