- In a study done on the zika virus, it was found that ivermectin was able to pass through the epithelial layer in the intestine when taken in the form of a pill (12 hours)
- Ivermectin partially inhibits the action of the NS1 protein and the functioning of IMPa-NLS in those with zika virus
- Ivermectin also prevents IMPa/B function in those with the dengue virus
- Effects of viral RNA was stopped due to ivermectin inhibiting NS3 helicase (found in those with west nile virus, yellow fever virus, and dengue virus)
- Ivermectin decreased the presence of the Hedra virus, Newcastle virus, and Venezuelan equine encephalitis virus substantially
- In the chikungunya virus, ivermectin got rid of luciferase signaling (responsible for virus replication)

Michigan State University

- A majority of the COVID-19 virus in a person is killed in 2 days with ivermectin
- Avermectin --> Ivermectin
- When avermectin is converted into ivermectin. a double bond between two carbon atoms in a benzene ring becomes a single bond
- Ivermectin does not cause toxicity
- Ivermectin had no impact on ATPase
- In the viruses mentioned in the chart, they all have the same or similar characteristics as the coronavirus (enveloped, positive-sense, single stranded)
- Ivermectin is very potent and thus can inhibit RNA replication in both the positive and negative strand

Ivermectin's impact on several different viruses and its possible impact on the coronavirus

Heidary, F., & Gharebaghi, R. (2020). Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen. The Journal of Antibiotics, 1-10.

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