Competes with the original ligand for the same binding site on a receptor 

Competitive Ligand

- Binds to a receptor site different than the one of the original ligand (modulatory site)
- May either activate the receptor (noncompetitive agonist) or prevent receptor activation (competitive antagonist)
- Also called neuromodulator

Noncompetitive Ligand 

Endogenous Ligand

- Noncompetitive Ligand
- Competitive Ligand
- Endogenous Ligand 

Rutgers University

Any substance that binds to receptors, such as neurotransmitters 

Ligand

Breedlove, S. & Watson, N. (2017). Behavioral neuroscience, eighth edition. Oxford University Press.

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