Concept

Limitations of applying Glycyrrhizin's effect on SARS-CoV to SARS-CoV-2

The selectivity index from the study by Cinatl et al was calculated by testing Vero cells, and as learned from the misleading results of hydroxychloroquine working well for treating SARS-CoV-2 in Vero cells but not human cells, the possibility that glycyrrhizin works differently in Vero cells must be kept in mind. It is not known what the effects of glycyrrhizin are on SARS-CoV-2 replication, but because of the genetic similarity between SARS-CoV-2 and SARS-CoV, glycyrrhizin could potentially be effective in inhibiting SARS-CoV-2 replication.

0

1

Updated 2020-08-13

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences