RT4 cells that were pre-treated with anti-ACE2 antibodies were introduced to LMWHs.  Because dalteparin has an IC50 value of 0.558 U/ml, it may be potent enough to be used below the target dose prophylactically.  However, the same cannot be said for its therapeutic use.

Michigan State University

LMWHs include drugs such as dalteparin and enoxparin.

- Prophylactic concentration:  0.2-0.5IU/ml
- Therapeutic concentration: 0.5-1.2IU/ml 

IU: international units (arbitrary amount)

Prophylactic and Therapeutic Serum Concentrations of Low Molecular Weight Heparins (LMWH)

Two low molecular weight heparins (LMWH) were introduced to RT4 cells that were pre-treated with anti-ACE2 antibodies: dalteparin and enoxaparin.  They were reported to have IC50 values, a measurement of the potency of an inhibitor, of 0.558 and 0.072U/ml.  Both were found to be partial inhibitors and less potent than unfractionated heparin.  

Low Molecular Weight Heparins are Partial Inhibitors of SARS-CoV-2 S Protein

Partridge, L. J., Urwin, L., Nicklin, M. J., James, D. C., Green, L. R., & Monk, P. N. (2020). ACE2-independent interaction of SARS-CoV-2 spike protein to human epithelial cells can be inhibited by unfractionated heparin. bioRxiv.
https://www.biorxiv.org/content/10.1101/2020.05.21.107870v2
doi: 10.1101/2020.05.21.107870

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