Among critically ill COVID-19 patients, profound acute hypoxemic respiratory failure from acute respiratory distress syndrome (ARDS) is the dominant finding. General supportive care of the critically ill patient with COVID-19 pneumonia is similar to that in patients with ARDS due to other causes. Common complications of COVID-19-related ARDS include acute kidney injury, elevated liver enzymes, and cardiac injury (eg, cardiomyopathy, pericarditis, pericardial effusion, arrhythmia, sudden cardiac death).