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Concept
Measure exposure
The measurement of the exposure(s) must be collected in a comparable way for cases and controls. It is worth 'blinding' the data gatherers to case or control status of participants or at least blind them to the main hypothesis of the study. This should help prevent measurement or researcher bias. Exposure information can come from records (though, obvious disadvantage is that records can be inaccurate, incomplete and were not originially collected for the study purposes) or can be via an interview or questionnaire (this can introduce recall bias, where cases have more vested interest in recalling the exposures than controls, and sometimes rely on 'proxy' respondents, e.g. carers, or parents of children).
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Updated 2020-04-05
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Data Science