In TMS treatment of depression, continual, rapid electromagnetic stimulation given to the brain can lead to increased neuron activity as well as increased blood flow to the targeted region. 

Northwestern University

A non-invasive method of brain stimulation that relies on electromagnetic induction using an insulated coil placed over the scalp which creates a magnetic field to induce a small electric current in a specific part of the brain.

Transcranial Magnetic Stimulation 

Janicack, P.G., Dokucu, M.E. (2015). Transcranial Magnetic Stimulation for the treatment of major depression. Neuropsychiatr Dis Treat. 11, 1549-1560.

Transcranial magnetic stimulation for the treatment of major depression

Mayo Clinic Staff. (2023). Transcranial Magnetic Stimulation. The Mayo Clinic. https://www.mayoclinic.org/tests-procedures/transcranial-magnetic-stimulation/about/pac-20384625

Transcranial Magnetic Stimulation

Empirical evidence has shown statistically significant results supporting the efficacy of TMS in treatment of depression and improving depressive symptoms. Additionally, following completion of a course of TMS, effects have been shown to persist through 12 months after treatment. 

Efficacy of TMS in treatment of depression.

Mechanics of rapid, continual Transcranial Magnetic Stimulation treatment for depression

Potential Side Effects of Transcranial Magnetic Stimulation:
- Discomfort at the site of stimulation on scalp.
- Constricting of muscles surrounding eyes during stimulation.
- Headaches accompanied by a tension sensation. 
- Rarely, seizures. 

Potential Side Effects of Transcranial Magnetic Stimulation

Adjustable Parameters and Aspects of TMS include:
- Location on the scalp of the coil used to deliver stimulation
- Motor Threshold (MT)
- Intensity, Frequency, and duration of stimulus pulses
- Number of pulses

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