Mescaline is a hallucinogen that acts as a serotonin agonist.

Mescaline as a Serotonin Agonist

- Come from the Peyote cactus
- Naturally occurring hallucinogen
- Currently illegal

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- Ayahuasca
- LSD
- Psilocybin
- MDMA
- DMT
- Mescaline

Types of Psychedelics

Spielman, R. M., Jenkins, W. J., & Lovett, M. D. (2020, April 22). Psychology (2nd ed.). OpenStax. https://openstax.org/books/psychology-2e/pages/1-introduction

OpenStax Psychology (2nd ed.) Textbook

A brewed Amazonian drink with psychoactive properties made by boiling Banisteriopsis caapi vine and Psychotria viridis bush leaves ( which contains harmala alkaloids, which render the hallucinogenic component DMT orally active).  It was originally used by indigenous shamans for religious rituals and healing. Now it is being used for recreation, being incorporated into folk medicine, and treatment for addiction, anxiety, and depression. 

Ayahuasca

Psilocybin is a 5HT-2A (serotonin 2A) receptor agonist that is a naturally-occurring psychedelic compound. It is derived from over 200 species of fungi, many from the genus Psilocybe. A purified bioactive compound derived from medicinal mushrooms.

Psilocybin

Mescaline

- Psychedelic, hallucinagenic, man-made compound
- Impacts cognitive, emotional, and perceptual processes in the brain through binding to serotonin receptors
- Thought to improve cognition and may have a positive effect on mental health
- Currently illegal in the United States, however, LSD is increasing in its usage

LSD (Lysergic Acid Diethylamide) 

DMT, N,N-dimethyltryptamine is an endogenous hallucinogen that was synthesized in 1931 by Canadian chemist Richard Manske.

DMT 

MDMA, or 3,4-methylenedioxymethamphetamine, is a mild stimulant with perception-altering effects, commonly known as 'ecstasy' or 'Molly'. It is typically ingested in pill form and produces effects such as increased energy, feelings of pleasure, and emotional warmth. While it has stimulant properties, its classification is debated due to its hallucinogenic effects and chemical similarity to amphetamines.

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