In myasthenia gravis, autoantibodies block the receptors for acetylcholine (AChr) on muscle cells, resulting in paralysis.

University of Southern Mississippi

- Multiple sclerosis
- Myasthenia gravis
- Psoriasis
- Rheumatoid arthritis
- Systemic lupus erythematosus.

Types of Systemic Autoimmune Diseases

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Multiple sclerosis (MS) is an autoimmune central nervous system disease that affects the brain and spinal cord. Lesions in multiple locations within the central nervous system are a hallmark of multiple sclerosis and are caused by infiltration of immune cells across the blood-brain barrier.

Multiple sclerosis

Myasthenia gravis

Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales on elbows, knees, scalp, back, face, palms, feet, and sometimes other areas. Some individuals with psoriasis also get a form of arthritis called psoriatic arthritis, in which the joints can become inflamed. Psoriasis

Psoriasis

Rheumatoid arthritis is an example of an autoimmune disease that specifically targets the joints. This condition results in symptoms such as joint pain, stiffness, and a loss of function.

Rheumatoid Arthritis

Systemic lupus erythematosus (SLE), also known as lupus, is an autoimmune disease where the body's immune system attacks its own tissues, which can inflict permanent damage on multiple organs like the heart, lungs, and kidneys. The pathology of SLE is caused by type III hypersensitivity reactions, where autoantibodies are produced against nuclear and cytoplasmic proteins.

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