Psychobiotic research examines rodent behavior to measure changes in motivation, anxiety, and depression following treatment. In 2015, a study published in Neuroscience journal reported probiotic supplements improved resilience in rats following stressful experiences. Dosing stressed rats with Lactobacillus helveticus lowered anxiety and depression-like behaviors.

University of Illinois at Chicago

The antidepressant efficacy of probiotics and improved cognition is demonstrated in recent research. Multiple studies have reported improvements in symptoms of depression, anxiety, and cognition along with somatic components. 

Antidepressant Efficacy of Psychobiotics

Zhu, H., Tian, P., Zhao, J., Zhang, H., Wang, G., & Chen, W. (2022). A psychobiotic approach to the treatment of depression: A systematic review and meta-analysis. Journal of Functional Foods, 91, 104999.

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