- Coronavirus Disease 2019 Test Results After Clinical Recovery and Hospital Discharge Among Patients in China

Journal of American Medical Association References for COVID-19 Recovery & Rehabilitation 

- Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing

Cell Discovery References for COVID-19 Recovery & Rehabilitation

- Rehabilitation After Critical Illness in People With COVID-19 Infection

American Journal of Physical Medicine & Rehabilitation References for COVID-19 Recovery & Rehabilitation

- American Journal of Physical Medicine & Rehabilitation
- Cell Discovery
- Journal of American Medical Association (JAMA)



University of California, Davis

University of Michigan - Ann Arbor

Smith College

Due to the varying experiences for those with COVID-19, recovery and rehabilitation look different for many individuals. As a baseline, "for persons recovered from COVID-19 illness, CDC recommends that isolation be maintained for at least 10 days after illness onset and at least 3 days (72 hours) after recovery. Illness onset is defined as the date symptoms begin. Recovery is defined as resolution of fever without the use of fever-reducing medications with progressive improvement or resolution of other symptoms. Ideally, isolation should be maintained for this full period to the extent that it is practicable under rapidly changing circumstances."

COVID-19 Recovery & Rehabilitation

COVID-19 Recovery & Rehabilitation by Continent

References for COVID-19 Recovery & Rehabilitation Organized by Journal/Source 

A study conducted on 10 COVID-19 patients undergoing recovery examined the immune cell profile using a single-cell RNA sequencing technique. In comparison to healthy controls, it found that T cells and NK cells were significantly decreased and the number of myeloid cells and monocytes with high inflammatory gene expression increased. Plasma B cells were also increased to enhance production of antibodies. 

Transcriptome Profiling of COVID-19 Patients During Recovery Stage

Specialist intervention may be necessary due to:

- Reduced physical function following ARDS, which requires regular physical examinations to restore to normal capacity

- Post-ARDS impaired cognitive function and delurium in ICU patients. 

- Depression, PTSD, anxiety, and social stigma 

Obstacles to rehabilitation may include:

- Reduced staff availability

- Lack of PPE

- Lack of capacity at rehabilitation facilities

- Co-morbidities 

- Reinfection

Virtual rehabilitation is one option for healthcare providers to use to limit physical contact but may not provide the complete benefits of rehabilitation.

Rehabilitation after critical illness in patients with COVID-19

A study showed that SARS neutralizing antibodies can successfully block SARS-CoV-2 entry into target cells in vitro, suggesting that the two viruses possess a cross-protective epitope and have similar immune protection against reinfection

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