- Wang and colleagues suggest repurposing GC376 to prevent the proliferation of SARS-CoV-2 may be a very effective therapeutic target, as it has already shown to effectively prevent the proliferation of other coronaviruses. 

Santa Clara University

- Studies have demonstrated the ability of GC376 to prevent the proliferation of multiple human and animal coronaviruses.

The coronaviruses it has shown to prevent the proliferation of are:
- MERS-CoV
- SARS-CoV-1
- porcine epidemic diarrhea virus (PEDV)
- feline infectious peritonitis virus (FIPV)


GC376 Prevents the Proliferation of Multiple Coronaviruses

Wang, Y., Yang W., Chen Y. et al.(2020 Aug 1). Structural basis of SARS-CoV-2 main protease inhibition by a broad spectrum anti-coronaviral drug. American Journal of Cancer Research, 10(8): 2535-2545. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471349/pdf/ajcr0010-2535.pdf	


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