Samples collected from carrier parents and siblings of patients with biallelic mutations in AGSI-7 and ACP5 did not present an interferon signature. 

Tulane University

Control populations included a diverse population without preexisting medical conditions. Additionally, siblings and parents, with unaffected phenotypes, of patients were included as controls. 

Control Groups

Rice GI, Melki I, Frémond ML, Briggs TA, Rodero MP, Kitabayashi N, Oojageer A, Bader-Meunier B, Belot A, Bodemer C, Quartier P, Crow YJ. Assessment of Type I Interferon Signaling in Pediatric Inflammatory Disease. J Clin Immunol. 2017 Feb;37(2):123-132. doi: 10.1007/s10875-016-0359-1. Epub 2016 Dec 9. PMID: 27943079; PMCID: PMC5325846.

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