Once HIV has been converted into DNA, the HIV integrase enzyme can attach itself to the end of the DNA strands and pass through the cell nucleus wall. This will bind to the host cell DNA.

Integration

When HIV enters the cell, it must be reverse-transcribed into DNA to be integrated into the cells' DNA

State University of New York at Stony Brook

The First step is attachment and entry. HIV will infect the immune system cells (T-cells, monocytes, macrophages, and dendritic cells.) All of those cells have a CD4 receptor on the outside. When the virus makes contact with the CD4 receptor, the gp120 spikes on the outside of the virus will latch onto the CD4. This is a part of the fusion process.

The Life of HIV

The science of HIV and AIDS - overview. (2019, October 10). Retrieved from https://www.avert.org/professionals/hiv-science/overview#:~:text=When HIV RNA enters the,proviral DNA inside the cell.


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